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Distal conformational steering by N-terminal pyroglutamylation enables subtype-selective GPCR activation across Aplysia PRXamide and human Neuromedin U signaling

measurement

heat
43 / 100 (raw 1.7)
velocity
0.5 independent sources per hour
solidity
60 / 100
sources
1 total, 1 independent
domain span
0 domain covered it
entities

primary source

title
Distal conformational steering by N-terminal pyroglutamylation enables subtype-selective GPCR activation across Aplysia PRXamide and human Neuromedin U signaling
venue
bioRxiv
status
not peer-reviewed
doi
10.64898/2026.07.28.741146
published
2026-07-30